Children with autism have more connections between the hemispheres and within the frontal lobe

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We talked about the brain scan that was developed to detect autism in adults. Brain scans in children that carry an autism gene (CNTNAP2) are now providing very interesting results.  [PLEASE NOTE: Many people (about 1/3 the population) have this gene variant- without demonstrating the characteristics of autism.  The presence of this gene indicates the subject is at risk for autism.] There seems to be more connections among neurons in the frontal lobe.

This research under the direction of  Dr. Geschwind of UCLA employed 32 children as subjects, as they were learning various skills. All the children had the gene variant, but only half exhibited the symptoms of autism.  Using fMRI, the researchers found differences in the frontal lobe and between the frontal lobe and the rest (left and right sides) of the brain.  Whether or not autism was manifested, the frontal lobe was overconnected to itself, especially when compared to the pathways to the rest of the brain, with diminished communication to the rear of the brain.

Moreover, for the children not manifesting autism, the communication pathways linked to the left brain; those manifesting autism had links to both sides of the brain. (The left side of the brain controls language skills, such as speech and understanding; this change in linkage may explain the speech pathology of children with autism.)

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162 thoughts on “Children with autism have more connections between the hemispheres and within the frontal lobe”

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