Tag Archives: antibiotics

The Dirty Secret About Antibiotic Resistance

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We read almost every single week that a new drug has been developed to treat a chronic condition.  And, the price tag for this pharmaceutical miracle is $ 400K,  $ 1KK, or even $ 2KK.   That’s the pot at the end of the rainbow that all of our pharmaceutical houses are seeking.

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Let’s get MRSA!

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Here’s a new wrinkle.  Our antibiotics are compounds that interfere with bacterial cell wall production, membrane integrity, protein biosynthesis, and DNA synthesis.  But, given our overuse (and incomplete drug regimens), the microbes we hope to kill have already developed resistance to the antibiotics in our arsenal.

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eNTRyway

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I’ve written how we often discovered antibiotics.  Simple.  By sampling mud, ponds, habitats where microbes thrive and try to find the one strain that inhibits the growth of other microbes.  Not a very efficient process- and one that provides less benefit now that we’ve discovered a slew of microbes.  We just can’t seem to find a new one that works, to bolster our arsenal against disease.

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Hits you right in the gut

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A computational biologist, Arnau Vich Vila, presented his PhD research at the United European Gastroenterology conference in Barcelona (October 2019).  His paper, coauthored with his PhD advisor, Rinse K Weersma at the University Medical Center at Groningen, along with co-authors from Groningen (Netherlands), as well as from the Maastricht University Medical Center (also from the Netherlands)  , discussed the effects of various drug categories on the patency of our gut microbiome.

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